An Experienced CDMO Team


An Experienced CDMO Team

Wealth of experience taking large molecule drugs to market.

Scorpius BioManufacturing is an integrated CDMO focused on rapidly advancing your mammalian and microbial biologic programs to the clinic and beyond. With end-to-end capabilities from discovery to limited-scale commercial production, we provide a broad array of R&D, analytical testing, and manufacturing services to pharmaceutical and biotech companies. With an experienced team and new, purpose-built, U.S. facilities, Scorpius is dedicated to easily accessible, transparent collaboration and flexible biologics biomanufacturing. 

Biomanufacturing Services

Scorpius offers leading expertise for biologics manufacturing services, with all work carried out in Texas and focused on utilizing American-made equipment and reagents.

Commercial Manufacturing

Large-scale commercial manufacturing in planning and engineering phase: cGMP manufacturing for preclinical, clinical scale, and limited commercial-scale biologics.

Mammalian Cell Culture Process Development

Optimizing upstream processes, Scorpius uses miniaturized bioreactors from small-scale, preclinical evaluation to cGMP-compliant clinical & commercial-scale process development.

Microbial Fermentation Process Development

Scorpius utilizes expandable single-use stirred bioreactor systems to optimize microbial fermentation batch & fed-batch processes for protein biologics, therapeutic enzyme and plasmid DNA production.

Downstream Purification Process Development

Scorpius’ advanced protein characterization capabilities includes refolding of recombinant proteins that are expressed as insoluble inclusion bodies.

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Cell-Based Assays

We can validate custom cell-based assays in line with regulatory guidelines to develop what you need from categories including cell proliferation, cell death, cell signaling and reporter death.


Immunoassays are well suited to characterization of selected drug candidates or analysis during product optimization due to their sensitive, reproducible, high-throughput qualities.

Molecular Assays: qPCR

Our scientific team offers a depth of expertise in the development, optimization and validation of complex molecular assays using conventional and qPCR.

Bioanalytical Methods

Scorpius supports clients in all phases of drug development with bioanalytical techniques, including HPLC characterization, Biacore™ biomolecules interaction analysis, and fluorescent microscopy.

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State-of-the-Art Equipment

Explore the instrumentation and equipment technology that can power your project forward.

Analytical Technology
Process Development
Mammalian Cell Culture Development

Our cell culture process development spans all phases from small-scale preclinical evaluation to commercial-scale processes.

Process Development
Cell Therapy Development

Scorpius has extensive experience in the isolation of cells from a variety of tissue sources, as well as development of expansion and cell recovery processes.

Process Development
Microbial Fermentation Development

Scorpius offers development of recombinant E. coli fermentation processes for optimal expression of a range of different proteins, enzymes, toxins, and plasmid DNA.

Process Development
Downstream Purification

Scorpius offers experience in development of recovery and purification processes for a wide variety of proteins, enzymes, immunotoxins, monoclonal antibodies, and exosome products.

Process Development
Formulation Development

Scorpius offers expertise in this critical aspect of biopharmaceutical development programs, ensuring the quality, safety, and efficacy of drugs products.

Analytical Methods Development

Scorpius offers a wide range of analytical testing services with a phase-appropriate approach to method development, qualification, and validation.

Mammalian Cell Culture

Scorpius' new biologics manufacturing facility features nine cleanrooms for mammalian cell culture and harvest, downstream purification, formulation, and fill-finish.

Microbial Fermentation

A portion of our new biomanufacturing facility is dedicated to recombinant microbial protein and plasmid DNA production.


Clinical-Scale Biomanufacturing Facility

Scorpius completed construction of our new clinical scale biologics manufacturing facility in San Antonio, Texas in 2022, which is fully operational.

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~2,000 sq. ft.
of analytical development space
~8,000 sq. ft.
of cGMP-compliant cleanroom manufacturing space
Up to 500 L
scale for mammalian and cell-therapy based products capabilities
200 L
scale for microbial-based products capabilities

Work with Us

Scorpius BioManufacturing is a fast-growing clinical biomanufacturing business in San Antonio, Texas, and we are looking to grow our talented team. If this sounds of interest to you, make the jump to our careers page.

Explore Opportunities

Contact Us

Scorpius is headquartered in San Antonio, Texas, in the heart of a rapidly growing hub for biotechnology and life sciences. With strong investment in science in the region, and a thriving community among biotechs, Scorpius is building on its roots as a team that has developed monoclonal antibodies and fusion protein-based biologics to be a technologically advanced CDMO. Reach out to us today. You’ll get a warm welcome in Texas.

Scorpius BioManufacturing
1305 East Houston Street
San Antonio, TX 78205, USA