Scorpius has designed ~5,400 sq. ft. of its San Antonio-based contract biomanufacturing facility for mammalian cell culture and harvest, downstream purification, formulation, and fill-finish operations.
The biologics CMO facility contains nine cGMP-compliant controlled cleanrooms with dedicated air handling units designed for maximal segregation. Each of these cleanroom areas is designed for maximum flexibility in mind, with much of the equipment on wheels for easily customized room formats.
As is the case with the rest of our facility, the cleanrooms use American-made equipment and consumables, with many supplied mechanicals made on-site. Every modular cleanroom area in Scorpius' facility includes water for injection (WFI) drops as needed along with multiple electrical and process gas drops for:
Cell harvesting systems
Downstream filtration systems
The controlled areas are designed for unidirectional flow of personnel, raw materials, intermediates, product, and waste. The material finishes used on the cleanroom walls, floors and ceilings were selected for ease of cleaning and are suited to cGMP-compliant biomanufacturing.
Scorpius BioManufacturing's cGMP-compliant mammalian cell culture facilities are equipped with bioreactors with capacities of 50, 200, 500 L, including the Pall Allegro™ STR single-use family of stirred tank bioreactors.